The key to alternate picking with the guitar pick when dealing with jazz improvisation and jazz fusion improvisation is to be aware of the off -beat. In these two little examples we simply miss the 1st beat.
Remember that the 2nd note of a group of 16ths will be an “Off-beat” and an “Upstroke”. But, if you start on the “Off-beat” with a down stroke then the patterns will be opposite to what they would be starting on the beat. This may sound confusing but is “paradoxically” natural and an easy way to create and control ‘syncopation”, literally cutting off the first note.
You can do this anywhere in the bar, but to begin with it is best explained through the two short example alternate picking exercises.
This phrase below is a little “Off-beat” phrase found in the John Mclaughlin album/CD called “Belo Herozonte.
Below we use sextuplets and miss out the first beat. [Count the silent beat but pluck the string starting on the 2nd off beat].